CD11a expression distinguishes infiltrating myeloid cells from plaque‐associated microglia in Alzheimer's disease
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چکیده
منابع مشابه
From heterogeneous patient measurements towards earlier diagnosis in Alzheimers disease
European funded project PredictAD has developed a decision support tool for objective diagnostics of Alzheimer’s disease. The tool compares measurements of a patient to measurements of other persons available in large databases and provides a simple index about the severity of the disease. The project has shown that the tool improves the accuracy of diagnosis and clinicians’ confidence about th...
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The CD11a/CD18 (leukocyte function-associated antigen 1 [LFA-1]) integrin mediates critical leukocyte adhesive interactions during immune and inflammatory responses. The CD11a promoter directs CD11a/CD18 integrin expression, and its activity in lymphoid cells depends on a functional RUNX1/AML-1-binding site (AML-110) within the MS7 sequence. We now report that MS7 contains a C/EBP-binding site ...
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ژورنال
عنوان ژورنال: Glia
سال: 2018
ISSN: 0894-1491,1098-1136
DOI: 10.1002/glia.23575